Wilkes University

September

Research Opportunities with Pharmacy Practice Faculty

Some of the projects announced on Tuesday have specific requirements in terms of level of student needed. This has been added to the descriptions below.

The following faculty have potential research opportunities for student pharmacists. Please contact them directly for more information.

Faculty Dr. Scott Bolesta

Research Focus: Determine the pharmacokinetics and pharmacodynamics of vitamin C in cardiac surgery patients.

Research Overview: Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery that increases the incidence of stroke, kidney injury and death. Vitamin C has been shown to decrease the incidence of POAF follow cardiac surgery, but the optimal dose has not been identified. With this project we plan to gather pharmacokinetic and dose-response data for vitamin C in the cardiac surgery population. We plan to conduct a small interventional pilot study investigating the pharmacokinetics and pharmacodynamics of Vitamin C in patients undergoing coronary artery bypass graft (CABG) surgery. Patients enrolled will receive an intravenous dose of Vitamin C the day before surgery and the day after. They will have blood samples obtained with each dose for analysis of vitamin C concentrations and several biomarkers of oxidative stress. Analysis of samples will be performed within the Department of Pharmaceutical Sciences at Wilkes University. The data from this study will support a NIH proposal to conduct a similar study in a larger sample, with the long-term goal of identifying an optimal vitamin C dose to prevent POAF in the cardiac surgery population.

Level of Students: P1
Number of Students on Project
2
Projected Time Commitment 3 hrs (1 credit).
Please note: if taking this for academic credit each credit hour requires 3 hours of work per week.

Faculty Dr. Dominick Trombetta

Research Focus: Relationship between the use of allopurinol and treatment for bpsd

Research Overview: New. Maybe mid semester before up and running. Expecting expedited IRB approval.

Level of Students: P2, P3
Number of Students on Project 3
Projected Time Commitment Unsure. Please note: if taking this for academic credit each credit hour requires 3 hours of work per week.

Faculty: Dr. Judith Kristeller

Research Focus: Improving medication management as patients transition from hospital to home.
Research Overview: This work is focused on identifying and preventing medication-related problems as patients transition from hospital to home. We focus on patients with 5 or more chronic medications and multiple chronic disease. Most of our students are work-study and help us with screening hospitalized patients for eligibility, starting the patient work-up, and collecting data on outcomes. Our APPE students meet with the patients and complete a comprehensive medication review. If you are interested in completing the internal medicine or research APPE at Moses Taylor Hospital or Regional Hospital of Scranton in the future, then this work will give you a nice head start. There are multiple opportunities for presenting abstracts at national meetings with our data on this research.

Level of Students: P2, P3
Number of Students on Project 5
Projected Time Commitment Flexible. Please note: if taking this for academic credit each credit hour requires 3 hours of work per week.

Faculty : Dr. Vicky Shah

Research Focus: Medication Use Evaluations (Variety of different medications/disease states)
Research Overview: Students will complete Medication Use Evaluations which entails retrospective chart reviews to determine if medications are being utilized and monitored appropriately. Some topics will require long term data collection and some will only have around 50 patients and can be completed in a short period of time.

Level of Students: P2, P3
Number of Students on Project 3
Projected Time Commitment Flexible. Please note: if taking this for academic credit each credit hour requires 3 hours of work per week.


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